Fluoride reduces the activity of cariogenic plaque. It shows bactericidal activity against testosterone cypionate vs enanthate microorganisms that appear when caries, inhibits the formation of lactic acid from carbohydrates. Fluorine ions directly affect the processes of mineralization of hard tissue of teeth during their development. The addition of fluoride provides education in the tissues of the teeth the most stable form of apatite fluorapatite.

At any incoming dose 50% fluorine accumulate in hard tissues of the tooth and bone. In the body of fluoride also accumulates in hair and nails. Not involved in the process of mineralization of fluoride excreted by the kidneys.

Indications
Prevention of dental caries in children aged 2 to 15 years (if the concentration of fluoride in drinking water is less than 0.7 mg / liter).

Contraindications
Hypersensitivity, hypothyroidism, testosterone cypionate vs enanthate gastric ulcer and duodenal ulcer (in the acute stage), liver and / or kidney failure, pregnancy, lactation. Living in an area with sufficient water fluoridation (above 0.7 mg / ml).

Dosing and Administration
The drug is taken orally, after meals. drinking water. Children aged 2 to 6 years 0.0011, the older at 0.0022 grams per day.

The course of treatment for at least 250 days a year, every year until the age of 15.

Side effects:
Allergic reactions (hud rash), rhinitis, nausea, vomiting, diarrhea, decreased appetite, fatigue, headache, eosinophilia, fluorosis (the appearance of yellow and brown spots, ispeshrennosti. Brittleness and abrasion of teeth).

An overdose of
the following symptoms are observed In case of overdose: melena, traces of blood in vomit, loss of appetite, abdominal pain, pain in the lower extremities, arthralgia, fatigue, cramps. visual impairment, myasthenia gravis, tremors, convulsions, fever, tachycardia, decreased blood pressure, the ossification of the tendons and ligaments attach the seats, hypothyroidism (with prolonged use).

Treatment: the introduction of large amounts of liquid and calcium (calcium gluconate solution or calcium lactate milk.) To precipitate fluorides induction of emesis, gastric lavage acidified water or a solution of 1% NaCl. appointment of laxatives (30 g sodium sulphate), in / in the introduction of electrolyte (20 mL of 10-20% calcium gluconate solution), vitamins: symptomatic therapy, monitoring of calcium levels in the blood; hemodialysis.

The interaction with other drugs
Vitamins A and D contribute to the development of ectopic calcification.

Cautions
Do not exceed the recommended dose or observe the dentist. Ensure that. the child did not get fluoride in addition, at the same time taking other drugs or supplements.

Children under 10 years should not be given the drug in a dose of 1 mg / day (the likelihood testosterone cypionate vs enanthate of developing dental fluorosis). The use in children under 6 years of age require special monitoring.

Product form
10 tablets in blisters.

5 contour cell package together with instructions for use placed in a cardboard box.